CPC C07K 14/635 (2013.01) [A61K 38/00 (2013.01)] | 20 Claims |
1. An isolated, unnatural peptide analogue comprising:
PTH, a parathyroid hormone receptor (PTHR-1, PTHR-2) agonist-effective fragment of PTH, a parathyroid hormone related protein (PTHrP), a PTHR-1 or PTHR-2 agonist-effective fragment of PTHrP, M-PTH, a PTHR-1 or PTHR-2 agonist-effective fragment of M-PTH, abaloparatide (BA058), or a PTHR-1 or PTHR-2 agonist-effective fragment of abaloparatide, in which at least one naturally occurring (L)-α-amino acid residue at position 6 or 7 from the N-terminus is replaced with a β-amino acid residue; and
salts thereof.
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