CPC C07C 245/16 (2013.01) [B01J 8/1881 (2013.01); B01J 19/0093 (2013.01); C07C 2/86 (2013.01); B01J 2208/00858 (2013.01); B01J 2219/00867 (2013.01); B01J 2219/00889 (2013.01); C07C 2523/44 (2013.01); C07C 2601/02 (2017.05)] | 19 Claims |
1. A process for the continuous production of a reaction product of a diazo compound and a substrate in a multi-stage continuous flow reactor comprising at least two connected reactors in fluid communication with each other, wherein a reaction product formed at each stage of the multistage sequence is continuously discharged from an upstream reactor in which it is formed, and is fed as a continuous fluid stream into a downstream reactor whereupon it can undergo further conversion, the process being characterized in that a precursor compound of the diazo compound that is continuously formed in an upstream reactor is continuously discharged into a downstream reactor under conditions conducive to convert it into the diazo-compound, and wherein said downstream reactor contains the substrate with which the diazo-compound reacts to form the reaction product of the diazo compound and the substrate.
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