US 11,779,682 B2
Electro-mechanically stretched micro fibers and methods of use thereof
Sharon Gerecht, Severna Park, MD (US); Shuming Zhang, Lehigh Acres, FL (US); Sebastian F. Barreto Ortiz, Baltimore, TX (US); and Hai-Quan Mao, Baltimore, MD (US)
Assigned to The Johns Hopkins University, Baltimore, MD (US)
Filed by THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US)
Filed on Oct. 5, 2018, as Appl. No. 16/152,556.
Application 16/152,556 is a continuation in part of application No. 14/398,072, granted, now 10,119,202, previously published as PCT/US2013/038805, filed on Apr. 30, 2013.
Claims priority of provisional application 61/665,498, filed on Jun. 28, 2012.
Claims priority of provisional application 61/640,057, filed on Apr. 30, 2012.
Prior Publication US 2019/0070339 A1, Mar. 7, 2019
Int. Cl. A61L 27/52 (2006.01); A61L 27/58 (2006.01); A61L 27/38 (2006.01); A61L 27/22 (2006.01); A61L 27/36 (2006.01); B82Y 5/00 (2011.01)
CPC A61L 27/52 (2013.01) [A61L 27/225 (2013.01); A61L 27/3633 (2013.01); A61L 27/3808 (2013.01); A61L 27/3826 (2013.01); A61L 27/3886 (2013.01); A61L 27/58 (2013.01); B82Y 5/00 (2013.01); A61L 2400/12 (2013.01); Y10T 428/29 (2015.01); Y10T 428/2913 (2015.01); Y10T 428/2922 (2015.01); Y10T 428/2938 (2015.01)] 34 Claims
OG exemplary drawing
 
1. A biodegradable microfiber having a longitudinally aligned nanotopography comprising biodegradable, electro-mechanically stretched, hydrogel, polymers, wherein alignment of the polymers is stabilized during gelation of the hydrogel.