CPC A61K 31/191 (2013.01) [A61P 25/20 (2018.01)] | 6 Claims |
1. A method of treating cataplexy or excessive daytime sleepiness in a human patient with narcolepsy, the method comprising:
determining the patient has an apnea/hypopnea index equal to or lower than 15;
prescribing to the patient a once-nightly formulation that, after oral administration, releases gamma-hydroxybutyrate into the bloodstream of the patient, wherein the formulation includes an immediate-release portion and a modified-release portion, wherein each once-nightly dosage of the formulation releases an amount of gamma-hydroxybutyrate into the bloodstream equivalent to 3 g to 9 g of sodium oxybate, and wherein the prescribing takes place after the determining; and
instructing the patient to take the formulation only once per night while in bed and to lie down immediately after dosing.
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