CPC A61K 8/0254 (2013.01) [A61K 8/025 (2013.01); A61K 8/585 (2013.01); A61K 8/965 (2013.01); A61Q 1/12 (2013.01); A61K 2800/26 (2013.01); A61K 2800/412 (2013.01); A61K 2800/621 (2013.01)] | 15 Claims |
1. A method of preparing composite particles comprising a non-porous spherical particulate inorganic material deposited on a plate-like inorganic material, where refractive index of said particulate inorganic material is greater than that of said plate-like inorganic particulate material, wherein, said spherical material occupies 20 to 80% of total surface area of said plate-like material and wherein the amount of said spherical material accounts for 2 to 20 wt % of said composite particles, further wherein said plate-like inorganic material is mica and said non-porous spherical particulate inorganic material is silicon dioxide, said method comprising the steps of:
(i) silanization of said plate-like inorganic material to get a silanized material having functional groups “A”;
(ii) silanization of said non-porous spherical particulate inorganic material to get a silanized material having functional groups “B”, where “A”≠“B”; and where said “A” and said “B” are capable of reacting with each other such that by way of their reaction, said non-porous spherical particulate inorganic material deposits on said plate-like inorganic material; and,
(iii) reacting said silanized material having functional groups “A” with said silanized material having functional groups “B”.
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