US 11,779,446 B2
Oral compositions and methods of use
Katie F. Wlaschin, St. Paul, MN (US); Amanda C. Engler, Woodbury, MN (US); Hannah C. Cohen, St. Paul, MN (US); Yizhong Wang, Woodbury, MN (US); Tao Gong, Woodbury, MN (US); Tiffany T. Ton, Woodbury, MN (US); Joel D. Oxman, Minneapolis, MN (US); Jie Yang, Woodbury, MN (US); and Richard P. Rusin, Woodbury, MN (US)
Assigned to 3M INNOVATIVE PROPERTIES COMPANY, St. Paul, MN (US)
Filed by 3M INNOVATIVE PROPERTIES COMPANY, St. Paul, MN (US)
Filed on Nov. 20, 2018, as Appl. No. 16/196,872.
Claims priority of provisional application 62/589,278, filed on Nov. 21, 2017.
Prior Publication US 2019/0083220 A1, Mar. 21, 2019
This patent is subject to a terminal disclaimer.
Int. Cl. A61C 19/06 (2006.01); A61P 1/02 (2006.01); A61K 36/00 (2006.01); A61Q 11/00 (2006.01); A61K 9/12 (2006.01); A61K 8/25 (2006.01); A61K 8/41 (2006.01); A61K 8/73 (2006.01); A61K 8/92 (2006.01); A61K 47/12 (2006.01); A61K 9/107 (2006.01); A61K 47/26 (2006.01); A61K 8/81 (2006.01); A61K 8/06 (2006.01); A61K 9/00 (2006.01); A61K 47/10 (2017.01); A61K 8/37 (2006.01); A61K 36/185 (2006.01); A61K 47/36 (2006.01); A61K 47/44 (2017.01); A61K 36/28 (2006.01); A61K 36/63 (2006.01); A61K 31/025 (2006.01); A61K 31/075 (2006.01); A61K 31/164 (2006.01); A61K 31/198 (2006.01); A61K 31/205 (2006.01); A61K 31/355 (2006.01); A61K 31/714 (2006.01); A61K 31/728 (2006.01); A61K 36/48 (2006.01); A61K 36/52 (2006.01); A61K 36/736 (2006.01); A61K 36/752 (2006.01); A61K 36/81 (2006.01)
CPC A61C 19/063 (2013.01) [A61K 8/062 (2013.01); A61K 8/25 (2013.01); A61K 8/375 (2013.01); A61K 8/41 (2013.01); A61K 8/73 (2013.01); A61K 8/731 (2013.01); A61K 8/732 (2013.01); A61K 8/737 (2013.01); A61K 8/8147 (2013.01); A61K 8/8176 (2013.01); A61K 8/922 (2013.01); A61K 9/006 (2013.01); A61K 9/0053 (2013.01); A61K 9/107 (2013.01); A61K 9/12 (2013.01); A61K 31/025 (2013.01); A61K 31/075 (2013.01); A61K 31/164 (2013.01); A61K 31/198 (2013.01); A61K 31/205 (2013.01); A61K 31/355 (2013.01); A61K 31/714 (2013.01); A61K 31/728 (2013.01); A61K 36/00 (2013.01); A61K 36/185 (2013.01); A61K 36/28 (2013.01); A61K 36/48 (2013.01); A61K 36/52 (2013.01); A61K 36/63 (2013.01); A61K 36/736 (2013.01); A61K 36/752 (2013.01); A61K 36/81 (2013.01); A61K 47/10 (2013.01); A61K 47/12 (2013.01); A61K 47/26 (2013.01); A61K 47/36 (2013.01); A61K 47/44 (2013.01); A61P 1/02 (2018.01); A61Q 11/00 (2013.01)] 21 Claims
 
1. A method of reducing one or more symptoms associated with one or more of xerostomia and dry mouth, the method comprising:
contacting an oral tissue with an edible oil-in-water composition,
the edible oil-in-water composition comprising:
an oil phase comprising:
one or more plant-based oils present in a total amount from 5 wt-% to 30 wt-% based on the total weight of the edible oil-in-water composition;
an aqueous phase comprising:
water,
wherein the aqueous phase is present in an amount from 70 wt-% to 95 wt-% based on the total weight of the edible oil-in-water composition;
one or more polyglycerol ester surfactant present in a total amount from 0.1 wt-% to 2 wt-% based on the total weight of the edible oil-in-water composition,
viscosity modifiers present in a total amount from 0.05 wt % to 3 wt-% based on the total weight of the composition,
wherein at least one viscosity modifier is ethyl cellulose, and
wherein at least one viscosity modifier is selected from hydroxypropyl guar and xanthan gum,
wherein the edible oil-in-water composition is characterized by a pH from 4.5 to 9.5.