US 12,437,399 B2
System and method for location insensitive reporting of fractional flow reserve-computed tomography for a given stenosis
Prem Venugopal, Clifton Park, NY (US)
Assigned to GE Precision Healthcare LLC, Wauwatosa, WI (US)
Filed by GE Precision Healthcare LLC, Wauwatosa, WI (US)
Filed on Apr. 14, 2023, as Appl. No. 18/134,774.
Prior Publication US 2024/0346644 A1, Oct. 17, 2024
Int. Cl. G06T 7/00 (2017.01); G06T 7/70 (2017.01); G16H 50/50 (2018.01)
CPC G06T 7/0012 (2013.01) [G06T 7/70 (2017.01); G16H 50/50 (2018.01); G06T 2207/10081 (2013.01); G06T 2207/30104 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A computer-implemented method for location insensitive reporting of a fraction flow reserve (FFR) value for a given stenosis, comprising:
obtaining, at a processor, vascular image data from a subject;
identifying, via the processor, a stenosed region within a vessel in the vascular image data;
generating, via the processor, a revascularized model of the vessel based on the vascular image data, wherein in the revascularized model a lumen boundary in the stenosed region is adjusted to have a same cross-sectional area as healthy sections of the vessel both proximal and distal to the stenosed region;
determining, via the processor, a first pressure distribution for the revascularized model at hyperemic flow;
determining, via the processor, a second pressure distribution for the vessel in the vascular image data;
calculating, via the processor, a subtracted pressure distribution by subtracting the second pressure distribution from the first pressure distribution;
determining, via the processor, an asymptotic value for the subtracted pressure distribution;
calculating, via the processor, a value by subtracting the asymptotic value from a pressure value obtained from the second pressure distribution at a location at a beginning of the stenosed region in the vessel; and
normalizing, via the processor, the value to obtain a location independent FFR value for the stenosed region.