US 12,437,395 B2
Image processing method, fertilized egg evaluation method and recording medium
Ryo Hasebe, Kyoto (JP)
Assigned to SCREEN HOLDINGS CO., LTD., Kyoto (JP)
Filed by SCREEN HOLDINGS CO., LTD., Kyoto (JP)
Filed on Aug. 10, 2022, as Appl. No. 17/885,055.
Claims priority of application No. 2021-142422 (JP), filed on Sep. 1, 2021; and application No. 2021-177900 (JP), filed on Oct. 29, 2021.
Prior Publication US 2023/0061181 A1, Mar. 2, 2023
Int. Cl. G06T 7/00 (2017.01); G06T 7/11 (2017.01)
CPC G06T 7/0012 (2013.01) [G06T 7/11 (2017.01); G06T 2200/04 (2013.01); G06T 2207/10101 (2013.01); G06T 2207/20152 (2013.01); G06T 2207/30024 (2013.01); G06T 2207/30044 (2013.01)] 16 Claims
OG exemplary drawing
 
1. An image processing method, comprising:
obtaining three-dimensional image data representing a three-dimensional image of a fertilized egg in a cleavage stage obtained by imaging the fertilized egg by optical coherence tomography;
extracting a blastomere region corresponding to an individual blastomere in the three-dimensional image for each blastomere based on the three-dimensional image data;
obtaining a volume of each extracted blastomere region based on the three-dimensional image data; and
obtaining an index value expressing a volume variation of the blastomeres based on the obtained volumes of the extracted blastomere regions,
wherein the volumes of the individual blastomere regions are normalized by an average or median value of the volumes of all the blastomere regions and the index value is obtained based on the normalized volumes.