US 12,436,317 B2
High throughput screening system for engineered cardiac tissues
Thomas Bifano, Mansfield, MA (US); Jerome Mertz, Newton, MA (US); Marshall Ma, Watertown, MA (US); and Devin Beaulieu, Brookline, MA (US)
Assigned to Trustees of Boston University, Boston, MA (US); and Massachusetts Institute of Technology, Cambridge, MA (US)
Filed by Trustees of Boston University, Boston, MA (US); and Massachusetts Institute of Technology, Cambridge, MA (US)
Filed on Jul. 18, 2023, as Appl. No. 18/223,289.
Claims priority of provisional application 63/390,469, filed on Jul. 19, 2022.
Prior Publication US 2024/0027655 A1, Jan. 25, 2024
Int. Cl. G02B 21/00 (2006.01); G02B 3/00 (2006.01); G02B 13/22 (2006.01); G02B 21/06 (2006.01); G02B 19/00 (2006.01)
CPC G02B 3/0037 (2013.01) [G02B 13/22 (2013.01); G02B 19/0047 (2013.01); G02B 21/0076 (2013.01); G02B 21/06 (2013.01)] 21 Claims
OG exemplary drawing
 
1. An imaging system comprising:
a light source configured to illuminate directly a plurality of spatially separated regions to generate a first illumination, each of the spatially separated regions including a material surface;
a lens array that includes one or more achromatic doublet lenses for magnifying the spatially separated regions, the lens array directly receiving the first illumination from the illuminating of the spatially separated regions, wherein the lens array generates a second illumination that magnifies the spatially separated regions, and wherein each lens of the lens array is concentrically aligned with a center of each of the spatially separated regions; and
a telecentric lens for directly receiving the second illumination from the lens array, wherein the telecentric lens directs the second illumination to a camera sensor to generate a mosaic image of the magnified spatially separated regions, and wherein the camera sensor records the mosaic image.