US 12,436,161 B2
Analysis device, analysis method, and analysis program
Masatoshi Ishiguro, Tokyo (JP); Miyuki Azuma, Tokyo (JP); Masayoshi Hayakawa, Gunma (JP); Hiroyuki Shimizu, Gunma (JP); and Kei Asano, Gunma (JP)
Assigned to PHC Corporation, Toon (JP)
Appl. No. 17/754,420
Filed by PHC Corporation, Toon (JP)
PCT Filed Oct. 2, 2020, PCT No. PCT/JP2020/037623
§ 371(c)(1), (2) Date Mar. 31, 2022,
PCT Pub. No. WO2021/066165, PCT Pub. Date Apr. 8, 2021.
Claims priority of application No. 2019-182496 (JP), filed on Oct. 2, 2019.
Prior Publication US 2022/0341960 A1, Oct. 27, 2022
Int. Cl. G01N 35/10 (2006.01); G01N 21/78 (2006.01); G01N 33/49 (2006.01); G01N 33/86 (2006.01)
CPC G01N 35/1016 (2013.01) [G01N 35/1011 (2013.01); G01N 2035/1023 (2013.01)] 6 Claims
OG exemplary drawing
 
1. An analysis device comprising a pierce nozzle, a sealed sample container in which a biological sample is contained, a predetermined container, a sample nozzle, one or more cuvette(s), an absorbance sensor configured to indicate a degree of coagulation of blood and a control device wherein the analysis device is configured to perform a plurality of measurement processing steps for the biological sample based on order information, the measurement processing steps comprising:
piercing with the pierce nozzle a hole in the sealed sample container in which the biological sample is contained, collecting the biological sample, and discharging the biological sample into the predetermined container;
dispensing from the sample nozzle the biological sample contained in the predetermined container into the one or more cuvettes; and
controlling with the control device operations of the pierce nozzle and the sample nozzle based on the order information,
wherein the control device is configured to discharge a volume of the biological sample from the pierce nozzle into the predetermined container, wherein the volume of the biological sample is not less than a total volume of a specimen required for each of the measurement processing steps included in the order information which includes one or more blood coagulation time measurement processing steps, and wherein the volume of the biological sample does not include a volume required for performing the blood coagulation time measurement processing step related to re-examination;
wherein the sample nozzle is configured to collect the biological sample from the sample container having an opening, and wherein a first position at which the pierce nozzle collects the biological sample from the sealed sample container is the same as the first position at which the sample nozzle collects the biological sample from the sample container having the opening; and
and wherein a second position of the predetermined container to which the biological sample is discharged from the pierce nozzle is the same as the second position of the sample container from which the sample nozzle collects the biological sample.
 
5. An analysis method executed by an analysis device configured to perform a plurality of measurement processing steps for a biological sample based on order information, comprising:
piercing with a pierce nozzle a hole in a sealed sample container in which the biological sample is contained, collecting the biological sample, and discharging the biological sample into a predetermined container containing unit; and
dispensing from a sample nozzle unit dispensing the biological sample contained in the predetermined container into one or more cuvette(s), wherein:
a volume of the biological sample which is discharged from the pierce nozzle unit into the predetermined container is not less than a total volume of a specimen required for each of the measurement processing steps included in the order information which includes one or more blood coagulation time measurement processing steps, and wherein the volume of the biological sample does not include a volume required for performing the blood coagulation time measurement processing step related to re-examination;
the sample nozzle is configured to collect the biological sample from the sample container having an opening, and a first position at which the pierce nozzle unit collects the biological sample from the sealed sample container is the same as a first position at which the sample nozzle collects the biological sample from the sample container having the opening; and
a second position of the predetermined container to which the biological sample is discharged from the pierce nozzle is the same as a second position of the predetermined container from which the sample nozzle collects the biological sample.
 
6. A non-transitory computer readable medium that comprises a memory encoded with an analysis program configured to cause an analysis device configured to perform a plurality of measurement processing steps for a biological sample based on order information to execute the following steps:
piercing a hole with a pierce nozzle in a sealed sample container in which the biological sample is contained, collecting the biological sample, and discharging the biological sample into a predetermined container; and
dispensing with the sample nozzle the biological sample contained in the predetermined container into one or more cuvette(s), wherein
discharging a volume of the biological sample from the pierce nozzle into the predetermined container is not less than a total volume of a specimen required for each of the blood coagulation time measurement processing steps included in the order information which includes one or more blood coagulation time measurement processing steps, and the volume of the biological sample does not include a volume required for performing the measurement processing step related to re-examination;
the sample nozzle is configured to collect the biological sample from the sample container having an opening, and wherein a first position at which the pierce nozzle collects the biological sample from the sealed sample container is the same as a first position at which the sample nozzle collects the biological sample from the sample container having the opening; and
wherein a second position of the predetermined container to which the biological sample is discharged from the pierce nozzle is the same as a second position of the predetermined container from which the sample nozzle collects the biological sample.