US 12,436,101 B2
Microscopy unit
Amitai Franklin, Tel Aviv (IL); Trevor Ruggiero, Somerville, MA (US); Sarah Levy, Jaffa (IL); Joseph Joel Pollak, Neve Daniel (IL); Aidan John Carroll, Anchorage, AK (US); Sharon Pecker, Rehovot (IL); and Yochay Shlomo Eshel, Sde Warburg (IL)
Assigned to S.D. Sight Diagnostics Ltd., Tel Aviv (IL)
Filed by S.D. Sight Diagnostics Ltd., Tel Aviv (IL)
Filed on Jun. 9, 2022, as Appl. No. 17/836,561.
Application 17/836,561 is a continuation of application No. PCT/IB2020/061731, filed on Dec. 10, 2020.
Claims priority of provisional application 62/946,986, filed on Dec. 12, 2019.
Claims priority of provisional application 62/947,001, filed on Dec. 12, 2019.
Prior Publication US 2022/0299436 A1, Sep. 22, 2022
Int. Cl. G02B 21/02 (2006.01); G01N 21/31 (2006.01); G01N 21/3577 (2014.01); G02B 21/36 (2006.01)
CPC G01N 21/3577 (2013.01) [G01N 21/314 (2013.01); G02B 21/02 (2013.01); G02B 21/361 (2013.01); G02B 21/362 (2013.01); G01N 2021/3148 (2013.01)] 19 Claims
OG exemplary drawing
 
1. An Apparatus for use with a microscopy unit that comprises an objective lens and a microscope camera, and for use with a bodily sample that contains an analyte disposed within water, the apparatus comprising:
a cantilever comprising an objective lens housing;
a motor configured to move the cantilever along a direction of an optical axis of the objective lens;
a sample chamber configured to receive the bodily sample, a height of the sample chamber being unknown;
an optical-density-measurement unit comprising:
one or more light sources configured to:
direct light through the sample at a first wavelength band, at which absorption of light by the analyte is relatively high, and
direct light through the sample at a second wavelength band that is centered around a wavelength of between 1.200 nm and 3,000 nm; and
one or more light detectors configured to detect light that passes through the sample at each of the first and second wavelength bands; and
at least one computer processor configured, based upon the detected light at each of the first and second wavelength bands, to determine a concentration of the analyte within the bodily sample, without directly measuring the height of the sample chamber.