US 12,436,068 B2
3D-printed mask for lysing at a location on a tissue section
Philipp Ott, Steg (CH); Patrick Kinney, Hayward, CA (US); and Adrian Sager, Männedorf (CH)
Assigned to TECAN TRADING AG, Männedorf (CH)
Appl. No. 18/723,218
Filed by TECAN TRADING AG, Männedorf (CH)
PCT Filed Dec. 22, 2022, PCT No. PCT/US2022/053758
§ 371(c)(1), (2) Date Jun. 21, 2024,
PCT Pub. No. WO2023/122243, PCT Pub. Date Jun. 29, 2023.
Application 18/723,218 is a continuation of application No. PCT/US2021/065085, filed on Dec. 23, 2021.
Prior Publication US 2024/0418611 A1, Dec. 19, 2024
Int. Cl. G01N 1/00 (2006.01); G01N 1/31 (2006.01)
CPC G01N 1/31 (2013.01) 18 Claims
OG exemplary drawing
 
1. A method for detaching tissue from a tissue section on a tissue slide, the method comprising:
(i) applying a 3D printed mask on top of the tissue section, the mask comprising barriers that define a cavity surrounding an area of interest on the tissue section, the cavity being open at a side facing the area of interest on the tissue section, wherein the 3D printed mask is 3D printed directly upon the tissue section,
(ii) dispensing a detaching liquid to the cavity, and allowing the detaching liquid to detach tissue at the area of interest, and
(iii) aspirating the detaching liquid with the detached tissue from the cavity, and forwarding the liquid for further processing.