US 12,435,357 B2
Diagnostic device for detecting a target nucleic acid molecule in a biological sample
Roy Rabinowitz, Tel Aviv-Jaffa (IL); and Omer Stoller, Ramat Gan (IL)
Assigned to KANSO DIAGNOSTICS LTD., Ramat Gan (IL)
Filed by KANSO DIAGNOSTICS LTD., Ramat Gan (IL)
Filed on Dec. 22, 2022, as Appl. No. 18/087,147.
Prior Publication US 2024/0209418 A1, Jun. 27, 2024
Int. Cl. B01L 3/00 (2006.01); C12Q 1/6816 (2018.01); C12Q 1/6844 (2018.01); C12Q 1/6869 (2018.01)
CPC C12Q 1/6816 (2013.01) [B01L 3/502761 (2013.01); C12Q 1/6844 (2013.01); C12Q 1/6869 (2013.01); B01L 2200/026 (2013.01); B01L 2300/044 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/0848 (2013.01); B01L 2300/0861 (2013.01); B01L 2400/0622 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A diagnostic device, comprising:
a body comprising:
an inlet for receiving a solution comprising a biological sample comprising a target nucleic acid molecule;
a plurality of reaction chambers, in liquid connection to the inlet, preloaded with nucleases capable of cleaving a nucleic acid molecule, into a first portion and a second portion;
a membrane placed between said plurality of reaction chambers and an informative chamber;
one or more valves located prior to said membrane,
and wherein said membrane has porosity sized to filter out molecules;
and wherein said informative chamber is configured to receive the filtered first portion, and wherein said informative chamber has at least one of,
a transparent region; and
a detector for detecting the marker.