US 12,435,318 B2
Reverse transcriptase mutants with increased activity and thermostability
Sarah Franz Beaudoin, Iowa City, IA (US); and Christopher Anthony Vakulskas, North Liberty, IA (US)
Assigned to INTEGRATED DNA TECHNOLOGIES, INC., Coralville, IA (US)
Filed by Integrated DNA Techonolgies, Inc., Coralville, IA (US)
Filed on Jul. 20, 2021, as Appl. No. 17/380,982.
Claims priority of provisional application 63/054,228, filed on Jul. 20, 2020.
Prior Publication US 2023/0031558 A1, Feb. 2, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. C12N 9/12 (2006.01); C12P 19/34 (2006.01); C12Q 1/686 (2018.01)
CPC C12N 9/1276 (2013.01) [C12P 19/34 (2013.01); C12Q 1/686 (2013.01)] 12 Claims
OG exemplary drawing
 
1. An isolated Moloney murine leukemia virus (MMLV) reverse transcriptase (RTase) mutant comprising the amino acid sequence of SEQ ID NO: 699.