	US 12,435,161 B2
	Process for direct sulfation of polysaccharides in an ecologically acceptable solvent
Paola Bazza, Desio (IT); Davide Bianchi, Desio (IT); and Auro Roberto Tagliani, Desio (IT)
Assigned to LESAFFRE ET COMPAGNIE, Paris (FR)
Appl. No. 17/905,337
Filed by LESAFFRE ET COMPAGNIE, Paris (FR)
PCT Filed Mar. 2, 2021, PCT No. PCT/IB2021/051714 § 371(c)(1), (2) Date Aug. 31, 2022, PCT Pub. No. WO2021/176341, PCT Pub. Date Sep. 10, 2021.
Claims priority of application No. 102020000004564 (IT), filed on Mar. 4, 2020.
Prior Publication US 2023/0090768 A1, Mar. 23, 2023
Int. Cl. C08B 37/00 (2006.01)

CPC C08B 37/0063 (2013.01) [C08B 37/0069 (2013.01); C08B 37/0075 (2013.01)]

10 Claims

1. A process for preparing chondroitin sulfates, said process comprising

reacting chondroitin or salts thereof with a sulfating agent, wherein said reacting step is carried out in acetic acid, under controlled temperature conditions.