	US 12,435,112 B2
	Adenovirus comprising a modified adenovirus hexon protein
Stefan Kochanek, Blaubeuren (DE); Lea Krutzke, Sachsenheim (DE); Robin Nilson, Ulm (DE); and Olivia Lübbers, Neu-Ulm (DE)
Assigned to UNIVERSITÄT ULM, Ulm (DE)
Appl. No. 17/769,689
Filed by UNIVERSITÄT ULM, Ulm (DE)
PCT Filed Oct. 20, 2020, PCT No. PCT/EP2020/079494 § 371(c)(1), (2) Date Apr. 15, 2022, PCT Pub. No. WO2021/078735, PCT Pub. Date Apr. 29, 2021.
Claims priority of application No. 19204420 (EP), filed on Oct. 21, 2019.
Prior Publication US 2022/0380411 A1, Dec. 1, 2022
Int. Cl. A61K 48/00 (2006.01); A61K 35/28 (2015.01); C07K 14/005 (2006.01); C12N 15/86 (2006.01)

CPC C07K 14/005 (2013.01) [A61K 35/28 (2013.01); C12N 15/86 (2013.01); C12N 2710/10322 (2013.01); C12N 2710/10332 (2013.01); C12N 2710/10343 (2013.01); C12N 2810/40 (2013.01)]

21 Claims

1. A human adenovirus species C comprising a capsid which comprises a modified adenovirus hexon protein, wherein the modified adenovirus hexon protein has a modified HVR1 region, wherein the modified HVR1 region comprises the sequence DEAATALEINLKKKKQAEQQ (SEQ ID NO.: 1).