US 12,434,247 B2
Method and device for extracting and/or reproducing a target nucleic acid
Simon Schmidbauer, Martinsried (DE); Juliane Duczek, Martinsried (DE); Cordula Urban, Martinsried (DE); Bettina Grotz, Martinsried (DE); Ricarda Mayer, Martinsried (DE); Eimantas Ruseckas, Martinsried (DE); Joachim Stehr, Martinsried (DE); Federico Bürsgens, Martinsried (DE); and Lars Ullerich, Martinsried (DE)
Assigned to HP Health Solutions Germany GmbH, Gräfelfing (DE)
Appl. No. 17/609,372
Filed by HP Health Solutions Germany GmbH, Gräfelfing (DE)
PCT Filed May 6, 2020, PCT No. PCT/EP2020/062531
§ 371(c)(1), (2) Date Nov. 18, 2021,
PCT Pub. No. WO2020/225286, PCT Pub. Date Nov. 12, 2020.
Claims priority of application No. 102019111841.7 (DE), filed on May 7, 2019; and application No. 102019114011.0 (DE), filed on May 24, 2019.
Prior Publication US 2022/0274116 A1, Sep. 1, 2022
Int. Cl. C12Q 1/686 (2018.01); B01L 7/00 (2006.01)
CPC B01L 7/52 (2013.01) [C12Q 1/686 (2013.01); B01L 2400/0445 (2013.01)] 24 Claims
OG exemplary drawing
 
1. A method for extracting a target nucleic acid from a sample liquid comprising:
providing a heating device having a heating element in contact with the sample liquid, wherein the heating element is conjugated with at least one functional nucleic acid, and wherein the at least one functional nucleic acid is adapted to hybridize with the target nucleic acid and bind the target nucleic acid to the heating element;
generating relative movement between the heating element and the sample liquid,
wherein the relative movement between the heating element and the sample liquid is generated at least in part by moving the heating element; and
extracting the target nucleic acid from the sample liquid by separating the heating element from the sample liquid.