US 12,434,240 B2
Flow cell comprising a storage zone and a duct that can be opened at a predetermined breaking point
Lutz Weber, Zweibrücken (DE)
Assigned to THINXXS MICROTECHNOLOGY GMBH, Zweibrücken (DE)
Filed by THINXXS MICROTECHNOLOGY GMBH, Zweibrücken (DE)
Filed on Mar. 21, 2023, as Appl. No. 18/187,560.
Application 18/187,560 is a continuation of application No. 16/203,039, filed on Nov. 28, 2018, granted, now 11,642,673.
Application 16/203,039 is a continuation of application No. 15/322,751, granted, now 10,173,215, previously published as PCT/EP2015/063992, filed on Jun. 22, 2015.
Claims priority of application No. 14175207 (EP), filed on Jul. 1, 2014.
Prior Publication US 2023/0219085 A1, Jul. 13, 2023
Int. Cl. B01L 3/00 (2006.01)
CPC B01L 3/502738 (2013.01) [B01L 3/502707 (2013.01); B01L 3/50273 (2013.01); B01L 3/523 (2013.01); B01L 2200/027 (2013.01); B01L 2200/028 (2013.01); B01L 2200/0689 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/123 (2013.01); B01L 2400/0481 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0655 (2013.01)] 7 Claims
OG exemplary drawing
 
1. A flow cell, comprising: an elongate storage chamber that is partially filled with a liquid fluid up to a fluid level and in which a pressurizable gas is enclosed above the fluid level directly bordering the gas; a lower duct that connects a lower end of the storage chamber to a chamber for receiving a specimen substance to be examined; an upper duct at an upper end of the elongate storage chamber; a barrier web that closes off the lower duct and the storage chamber, wherein the lower duct and the barrier web are arranged below the fluid level, wherein the barrier web has a predetermined breaking point formed by a material-locking connection that is; a film connected to the substrate so as to form the storage chamber and the ducts, wherein the breaking point is a material-locking connection that is irreversibly ruptured when the film is deflected; and a substantially plate-shaped substrate, wherein the storage chamber and the ducts are arranged in the substrate so that when the substrate is oriented vertically the liquid in the storage space escapes by gravity from the lower duct and a pressure is introducible from the upper duct so as to assist a flow of liquid, wherein the storage chamber has a stiff, inflexible wall so that positive and negative pressure is introduced to bull by external sources to facilitate the flow of the liquid.