US 12,434,238 B2
Imaging system and method for imaging biological samples transported in a fluid
Soeren Alsheimer, Wetzlar (DE)
Assigned to LEICA MICROSYSTEMS CMS GMBH, Wetzlar (DE)
Filed by LEICA MICROSYSTEMS CMS GMBH, Wetzlar (DE)
Filed on Dec. 12, 2022, as Appl. No. 18/079,020.
Claims priority of application No. 21215111 (EP), filed on Dec. 16, 2021.
Prior Publication US 2023/0191404 A1, Jun. 22, 2023
Int. Cl. B01L 3/00 (2006.01); G01N 15/14 (2024.01); G01N 15/10 (2006.01); G01N 15/1434 (2024.01)
CPC B01L 3/502715 (2013.01) [B01L 3/502761 (2013.01); G01N 15/1459 (2013.01); B01L 2400/0415 (2013.01); B01L 2400/0454 (2013.01); B01L 2400/0463 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/1447 (2013.01); G01N 2015/1452 (2013.01)] 14 Claims
OG exemplary drawing
 
1. An imaging system for imaging biological samples, the imaging system comprising:
at least one main channel comprising at least two imaging spaces, the at least one main channel configured to transport the samples in a fluid along a flow direction, wherein the at least two imaging spaces are separated apart from each other along the flow direction;
at least one reorientation unit configured to manipulate an orientation of the samples in the fluid, wherein the at least one reorientation unit is arranged between the at least two imaging spaces along the flow direction; and
at least one imaging unit configured to receive detection light emitted by the samples in at least one of the at least two imaging spaces.