US 12,434,223 B2
Zearalenone functionalized graphene surface molecularly imprinted material, preparation method therefor and use thereof
Changpo Sun, Beijing (CN); Yangying Han, Beijing (CN); Hujun Liu, Beijing (CN); Jun Wang, Beijing (CN); Xiaojiao Chang, Beijing (CN); and Jing Sun, Beijing (CN)
Assigned to Academy of National Food and Strategic Reserves Administration, Beijing (CN)
Appl. No. 17/927,384
Filed by ACADEMY OF NATIONAL FOOD AND STRATEGIC RESERVES ADMINISTRATION, Beijing (CN)
PCT Filed Jul. 1, 2021, PCT No. PCT/CN2021/104035
§ 371(c)(1), (2) Date Nov. 23, 2022,
PCT Pub. No. WO2022/007704, PCT Pub. Date Jan. 13, 2022.
Claims priority of application No. 202010641137.0 (CN), filed on Jul. 6, 2020; and application No. 202010641149.3 (CN), filed on Jul. 6, 2020.
Prior Publication US 2023/0234029 A1, Jul. 27, 2023
Int. Cl. B01J 20/26 (2006.01); B01D 15/18 (2006.01); B01D 15/20 (2006.01); B01J 20/10 (2006.01); B01J 20/20 (2006.01); B01J 20/28 (2006.01); B01J 20/289 (2006.01); B01J 20/30 (2006.01); B01J 20/32 (2006.01)
CPC B01J 20/268 (2013.01) [B01D 15/1807 (2013.01); B01D 15/206 (2013.01); B01J 20/103 (2013.01); B01J 20/205 (2013.01); B01J 20/28019 (2013.01); B01J 20/289 (2013.01); B01J 20/3021 (2013.01); B01J 20/3092 (2013.01); B01J 20/3204 (2013.01); B01J 20/3219 (2013.01); B01J 20/3278 (2013.01); B01J 2220/54 (2013.01)] 6 Claims
OG exemplary drawing
 
1. A zearalenone functionalized graphene surface molecularly imprinted material, which has reduced graphene oxide (RGO) as a carrier, cyclododecyl 2,4-dihydroxybenzoate (CDHB) as a template molecule, 1-allylpiperazine (1-ALPP) as a functional monomer, trimethylolpropane triacrylate (TRIM) as a cross-linking agent, azodiisobutyronitrile (AIBN) as an initiator, and acetonitrile as a pore-forming agent;
wherein the zearalenone functionalized graphene surface molecularly imprinted material is prepared by a preparation method comprising the following steps:
adding CDHB, 1-ALPP, TRIM, AIBN and acetonitrile to a solvent in sequence to provide a first mixture, mixing the first mixture uniformly, injecting nitrogen to remove oxygen and sealing the first mixture, and subjecting the first mixture to ultraviolet light irradiation for 24 h or 60° C. water bath for constant-temperature reaction for 24 h to obtain a molecularly imprinted polymer, wherein the solvent is N,N-dimethylformamide (DMF);
grinding the molecularly imprinted polymer, sieving it through a 100-200 mesh screen, and removing CDHB with an eluent to provide a product, drying the product at 40° C. overnight, to obtain a template-removed molecularly imprinted polymer; and
dispersing graphene oxide (GO) into water or DMF, adding the template-removed molecularly imprinted polymer to provide a second mixture, subjecting the second mixture to ultrasound and mixing it uniformly, then adding hydrazine hydrate to provide a third mixture, heating the third mixture in a 90-95° C. water bath for 4-6 h, cooling the third mixture to room temperature, filtering the third mixture to obtain a powder, then washing the powder with water and ethanol in sequence for a plurality of times, and drying the powder at 60° C. for 1-2 h to obtain the zearalenone functionalized graphene surface molecularly imprinted material.