US 12,434,068 B2
Accessing spinal networks to address sexual dysfunction
Daniel C. Lu, Los Angeles, CA (US)
Assigned to The Regents of the University of California, Oakland, CA (US)
Appl. No. 16/615,765
Filed by The Regents of the University of California, Oakland, CA (US)
PCT Filed May 22, 2018, PCT No. PCT/US2018/033942
§ 371(c)(1), (2) Date Nov. 21, 2019,
PCT Pub. No. WO2018/217791, PCT Pub. Date Nov. 29, 2018.
Claims priority of provisional application 62/510,245, filed on May 23, 2017.
Prior Publication US 2020/0155865 A1, May 21, 2020
Int. Cl. A61N 2/00 (2006.01); A61N 2/02 (2006.01)
CPC A61N 2/006 (2013.01) [A61N 2/02 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A method of improving or restoring sexual function in a subject with impaired sexual function, said method comprising:
determining a first frequency of a magnetic stimulation based on a plurality of bulbocavernosus reflex (BCR) measurements corresponding to an application of one or more frequency values;
applying the magnetic stimulation to the cervical and/or thoracic, and/or lumbosacral spinal cord wherein the magnetic stimulation is at the first frequency, the first frequency ranging from about 0.5 Hz up to about 100 Hz, and wherein the magnetic stimulation is sufficient to and effective to improve or restore a volitional control of sexual function in said subject;
repeatedly applying the magnetic stimulation at the first frequency after a first interval of time has passed, the first interval of time comprising one or more days until the volitional control of sexual function is achieved;
applying the magnetic stimulation to the cervical and/or thoracic, and/or lumbosacral spinal cord at a second frequency once the volitional control of sexual function is achieved, wherein the second frequency is less than the first frequency; and
repeatedly applying the magnetic stimulation at the second frequency at a second interval of time to maintain the volitional control of sexual function, wherein the second interval of time is longer than the first interval of time.