US 12,434,040 B2
Applicator for a microneedle array patch delivery system
Matthew Vargas, San Jose, CA (US); John Spiridigliozzi, Boston, MA (US); Harrison Wostein, Cambridge, MA (US); Michael Isidoro, Cambridge, MA (US); and Logan McElhinney, Cambridge, MA (US)
Assigned to VAXESS TECHNOLOGIES, INC., Cambridge, MA (US)
Filed by VAXESS TECHNOLOGIES, INC., Cambridge, MA (US)
Filed on Dec. 26, 2024, as Appl. No. 19/002,468.
Application 19/002,468 is a continuation in part of application No. PCT/US2024/034901, filed on Jun. 21, 2024.
Claims priority of provisional application 63/522,931, filed on Jun. 23, 2023.
Prior Publication US 2025/0128039 A1, Apr. 24, 2025
Int. Cl. A61M 37/00 (2006.01)
CPC A61M 37/0015 (2013.01) [A61M 2037/0023 (2013.01); A61M 2202/0007 (2013.01); A61M 2205/0216 (2013.01); A61M 2210/04 (2013.01)] 20 Claims
OG exemplary drawing
 
1. An applicator for applying a medicament patch to a subject comprising:
a top portion configured to be pressed downwards to activate an activation mechanism;
a bottom portion holding the medicament patch such that the medicament patch is suspended above a skin surface of the subject;
a middle portion connected to the top portion and the bottom portion, the middle portion comprising a plurality of flex arms configured to contribute about 6-15 lbs to an activation force of the activation mechanism;
a piston portion connected to the middle portion; and
a compressible member positioned between the middle portion and the piston portion;
wherein when the activation mechanism is activated, the piston portion is released from the top portion and the middle portion and moves downwards via force applied by the compressible member;
wherein, when the piston portion moves downwards, the medicament patch is released from the bottom portion and pushed downward by the piston portion directly contacting the medicament patch onto the skin surface of the subject.