| CPC A61M 5/31 (2013.01) [A61M 2005/3104 (2013.01)] | 12 Claims |

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1. A cap for a pre-filled syringe with a Luer-lock connector comprising: a main body provided with a first handle portion and a second portion configured to be coupled to said Luer-lock connector, an axial cavity having an aperture at said second coupling portion being formed in said main body; and a rubber housed within said axial cavity of said main body; wherein the cap comprises a tapered portion which is interposed between said first handle portion and said second coupling portion and is configured to air-tightly engage the Luer-lock connector, and said rubber has a surface facing the aperture of the axial cavity, said surface configured to abut against an open free end of a tip of the pre-filled syringe for air-tightly closing said open free end, wherein said rubber further comprises a series of longitudinal grooves formed in a side surface thereof.
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