US 12,433,996 B2
System and method for detecting issues in the basal rate in insulin treated diabetes patients
Fredrik Debong, Vienna (AT); Lukas Schuster, Vienna (AT); Jan Wrede, Salzgitter-Bad (DE); and Rafael Bankosegger, Vienna (AT)
Assigned to mySugr GmbH, Vienna (AT)
Filed by mySugr GmbH, Vienna (AT)
Filed on Jan. 14, 2021, as Appl. No. 17/149,398.
Application 17/149,398 is a continuation of application No. PCT/EP2019/069018, filed on Jul. 15, 2019.
Claims priority of application No. 18183576 (EP), filed on Jul. 15, 2018.
Prior Publication US 2021/0128833 A1, May 6, 2021
Int. Cl. A61M 5/172 (2006.01); A61M 5/142 (2006.01); A61M 5/168 (2006.01)
CPC A61M 5/1723 (2013.01) [A61M 5/142 (2013.01); A61M 5/16877 (2013.01); A61M 2205/52 (2013.01); A61M 2205/583 (2013.01)] 11 Claims
OG exemplary drawing
 
1. A system for determining a deficiency in a basal insulin infusion rate for a diabetic patient, comprising:
a diabetes management device;
a processor,
a display; and
a memory storing a program which causes the processor to execute the following steps:
a) receiving a plurality of measured glucose values, wherein each glucose value is associated with a measurement timestamp indicating a respective time and date of measurement; wherein step a) further comprises wirelessly or via wired transfer receiving the plurality of measured glucose values on the diabetes management device from a blood glucose meter for spot monitoring,
b) receiving, by the processor, meal and/or bolus event information wherein each of the meal and/or bolus event information is associated with an event timestamp indicating a respective time and date of a meal and/or bolus event,
c) determining whether the plurality of measured glucose values comprises at least n pairs of glucose values g01 to n and g11 to n, wherein n is at least 5, each pair x of glucose values fulfilling a predefined set of criteria obtained from the memory, wherein the predefined set of criteria includes the following requirements:
there are no measured glucose values with measurement timestamps between t0x and t1x of the pair x of glucose values,
a glucose value g0x of the pair x has the measurement timestamp t0x in a first predefined time of day range and a glucose value g1x has the measurement timestamp t1x within a first predefined temporal period relative to the measurement time stamp t0x,
no meal and/or bolus event information has its event timestamp between t0x and t1x,
no meal and/or bolus event information has its event timestamp in a second predefined temporal period relative to t0x, and
the glucose value g0x is within a predefined glucose value range;
d) determining pairing values based on the glucose values g0x and g1x of each pair x of the at least n pairs of glucose values, wherein the pairing value comprises the difference g1x-g0x of each of the at least n pairs of glucose values, and determining one or more statistical values based thereon; and
e) comparing the one or more statistical values to respective threshold values obtained from the memory, wherein exceeding or falling below one or more respective threshold values indicates a deficiency of the basal insulin infusion rate of the diabetic patient.