US 12,433,986 B2
Myocardial protection system
Ken Jones, McKinney, TX (US); Jeff Albertsen, McKinney, TX (US); Cristo Corera, McKinney, TX (US); and Lee Carter, McKinney, TX (US)
Assigned to QUEST MEDICAL, INC., Allen, TX (US)
Appl. No. 17/298,773
Filed by QUEST MEDICAL, INC., Allen, TX (US)
PCT Filed Dec. 17, 2019, PCT No. PCT/US2019/066989
§ 371(c)(1), (2) Date Jun. 1, 2021,
PCT Pub. No. WO2020/131967, PCT Pub. Date Jun. 25, 2020.
Claims priority of provisional application 62/782,143, filed on Dec. 19, 2018.
Claims priority of provisional application 62/781,301, filed on Dec. 18, 2018.
Prior Publication US 2022/0031923 A1, Feb. 3, 2022
Int. Cl. A61M 1/36 (2006.01)
CPC A61M 1/3664 (2013.01) [A61M 1/3607 (2014.02); A61M 1/362227 (2022.05); A61M 1/36224 (2022.05); A61M 1/36225 (2022.05); A61M 1/3666 (2013.01); A61M 1/369 (2013.01); A61M 1/362265 (2022.05); A61M 1/3623 (2022.05); A61M 2205/3331 (2013.01); A61M 2205/3368 (2013.01); A61M 2205/502 (2013.01)] 23 Claims
OG exemplary drawing
 
1. A cardioplegia delivery system comprising:
a console including:
a first pump to pump at least one of blood or crystalloid;
a second pump to pump an arrest drug;
a third pump to pump an additive;
a temperature controllable water circulation system configured to couple to a reservoir of coolant;
a first heat exchanger (HEX) to couple to the temperature controllable water circulation system;
a first sensor to sense pressure;
a second sensor to sense temperature;
a third sensor to sense air;
at least one processor-based computing node coupled to a graphical user interface (GUI), the at least one processor-based computing node and GUI being configured to separably couple to the console;
a second HEX;
a first container to include the crystalloid, a second container to include the arrest drug, and a third container to include the additive, wherein the first, second, and third containers are configured to releasably couple to the console;
at least one non-transitory machine-readable medium, wherein the at least one non-transitory machine-readable medium has stored thereon data which, if used by the at least one processor-based computing node, causes the at least one processor-based computing node to perform operations comprising:
control an amount of the arrest drug to be delivered to a patient;
control an amount of the additive to be delivered to the patient;
control a temperature of at least one of the crystalloid, the blood, the arrest drug, or the additive to be delivered to the patient;
control a pressure of at least one of the crystalloid, the blood, the arrest drug, or the additive to be delivered to the patient;
control a delivery rate of at least one of the crystalloid, the blood, the arrest drug, or the additive to be delivered to the patient;
record an amount of at least one of the arrest drug or the additive administered to the patient;
record an amount of time at least one of the crystalloid, the blood, the arrest drug, or the additive is administered to the patient;
in response to recording the amount of at least one of the arrest drug or the additive administered to the patient, determine a volume amount of the at least one of the arrest drug or the additive that remains and is available to be administered to the patient;
store at least one delivery protocol, the at least one delivery protocol including a predetermined setting for at least one of (a) pressure of at least one of the crystalloid, the blood, the arrest drug, or the additive to be delivered to the patient, (b) temperature of at least one of the crystalloid, the blood, the arrest drug, or the additive to be delivered to the patient, (c) flow rate of at least one of the crystalloid, the blood, the arrest drug, or the additive to be delivered to the patient, or (d) ratio of the crystalloid to the blood;
wherein: (a) in a first HEX orientation the first HEX sealingly couples to a port of the console and in a second HEX orientation the second HEX sealingly couples to the port of the console; (b) the first HEX includes a first amount of heat exchange baffling and the second HEX includes a second amount of heat exchange baffling, the second amount of heat exchange baffling being unequal to the first amount of heat exchange baffling, and (c) the port cannot operatively couple simultaneously to the first and second HEXs.