	US 12,433,971 B2
	Collagen reinforced tissue grafts
Thomas J. Koob, Marietta, GA (US)
Assigned to MiMedx Group, Inc., Marietta, GA (US)
Filed by MiMedx Group, Inc., Marietta, GA (US)
Filed on Mar. 19, 2020, as Appl. No. 16/823,616.
Application 16/823,616 is a division of application No. 14/838,305, filed on Aug. 27, 2015, granted, now 10,617,785.
Claims priority of provisional application 62/043,300, filed on Aug. 28, 2014.
Prior Publication US 2020/0215221 A1, Jul. 9, 2020
Int. Cl. A61L 15/40 (2006.01); A61L 15/32 (2006.01); A61L 27/24 (2006.01); A61L 27/36 (2006.01); A61L 27/54 (2006.01); A61L 31/04 (2006.01)

CPC A61L 15/40 (2013.01) [A61L 15/325 (2013.01); A61L 27/24 (2013.01); A61L 27/3604 (2013.01); A61L 27/3645 (2013.01); A61L 27/3675 (2013.01); A61L 27/54 (2013.01); A61L 31/044 (2013.01); A61L 2430/32 (2013.01); A61L 2430/40 (2013.01)]

19 Claims

1. A micronized composition comprising prepared by micronizing a multi-layered tissue graft, said multi-layered tissue graft comprising a collagen layer and at least one separated and washed placental tissue component and/or umbilical cord component, wherein the collagen layer is reconstituted, pepsin-cleaved human placental collagen substantially free of non-human antigens; and wherein the collagen layer is 10 to 80 wt % of the multi-layered tissue graft.