US 12,433,934 B2
Methods and compositions for preventing and treating atherosclerosis and related diseases
Yinghao Zhang, Shanghai (CN); Guirui Yan, Shanghai (CN); Yao Wang, Shanghai (CN); and Jingpeng Fu, Shanghai (CN)
Assigned to SHANGHAI PUYOU BIOMEDICAL CO., LTD., Shanghai (CN)
Filed by Shanghai Puyou Biomedical Co., Ltd., Shanghai (CN)
Filed on Mar. 10, 2021, as Appl. No. 17/198,034.
Application 17/198,034 is a continuation of application No. PCT/CN2019/105220, filed on Sep. 10, 2019.
Claims priority of application No. 201811052915.1 (CN), filed on Sep. 10, 2018.
Prior Publication US 2022/0040257 A1, Feb. 10, 2022
Int. Cl. A61K 38/17 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 9/10 (2006.01); C07K 14/47 (2006.01)
CPC A61K 38/1709 (2013.01) [A61P 9/10 (2018.01)] 3 Claims
 
1. A method for treating atherosclerosis or an atherosclerosis-related disease in a subject in need thereof, the method comprising:
administering to said subject an effective amount of secretory deleted split hand/split foot 1 (sDSS1) protein,
thereby treating said atherosclerosis or said atherosclerosis-related disease in said subject,
wherein said sDSS1 protein comprises an amino acid sequence of any one of SEQ ID NOs: 4-16.