US 12,433,923 B2
Processes for producing low chlorophyll, high polar lipid compositions from algal oils and extracts
Brian L. Goodall, Bretby (GB); Dmitry Kuklev, Ann Arbor, MI (US); and Glen L. Bostick, Columbia, IL (US)
Assigned to Nooter/Eriksen, Inc., Fenton, MO (US)
Filed by Nooter/Eriksen, Inc., Fenton, MO (US)
Filed on Jun. 30, 2023, as Appl. No. 18/216,965.
Application 18/216,965 is a continuation of application No. 17/718,009, filed on Apr. 11, 2022, granted, now 11,730,782.
Application 17/718,009 is a continuation in part of application No. 16/953,978, filed on Nov. 20, 2020, granted, now 11,298,387.
Prior Publication US 2023/0338446 A1, Oct. 26, 2023
Int. Cl. A61K 36/02 (2006.01); A61K 31/201 (2006.01); A61K 31/202 (2006.01)
CPC A61K 36/02 (2013.01) [A61K 31/201 (2013.01); A61K 31/202 (2013.01); A61K 2236/333 (2013.01); A61K 2236/39 (2013.01)] 5 Claims
 
1. A method for production of a low chlorophyll, enhanced polar lipids content oil composition comprising the steps of:
a. obtaining an algal oil or extract comprising a chlorophyll concentration and both polar and non-polar lipid fractions, wherein the polar lipid fraction is held within a polar solvent, and the non-polar lipid fraction is held within a non-polar solvent, and further wherein polar and non-polar lipids are more than 75% of the combined mass of the polar and non-polar lipid fractions;
b. using solvents of varying polarity, as well as polarity characteristics of the polar and non-polar lipid fractions, to separate polar from non-polar components in the algal oil or extract via multiple sequential extractions;
c. removing substantially all of the chlorophyll concentration from the non-polar containing fraction;
d. removing any remaining polar solvent, non-polar solvent, and solvents of varying polarity; and,
e. re-combining the polar and non-polar lipid fractions to produce the low chlorophyll content, enhanced polar lipids oil composition,
wherein water is not used during a first extraction of said multiple sequential extractions.