US 12,433,919 B2
Use of hemolymph or hemolymph components to regenerate, repair and restore the skin barrier
William Patrick Breeding, South Portland, ME (US)
Assigned to Marin Brands Inc., South Portland, ME (US)
Filed by Marin Brands Inc., South Portland, ME (US)
Filed on Sep. 3, 2021, as Appl. No. 17/466,139.
Claims priority of provisional application 63/074,089, filed on Sep. 3, 2020.
Prior Publication US 2022/0062351 A1, Mar. 3, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 35/612 (2015.01); A61K 8/98 (2006.01); A61K 38/00 (2006.01); A61Q 19/00 (2006.01); A61Q 19/08 (2006.01); C07K 14/435 (2006.01)
CPC A61K 35/612 (2013.01) [A61K 8/987 (2013.01); A61Q 19/007 (2013.01); A61Q 19/08 (2013.01); C07K 14/43509 (2013.01); A61K 38/00 (2013.01)] 23 Claims
 
1. A method for regenerating, repairing, or restoring the function of the skin barrier in a mammal, comprising the steps of:
(a) providing a composition consisting essentially of hemocyanin derived from organisms selected from the group consisting of:
lobster species selected from Nephrops novegicus, Homarus gammarus, or Panularis elephas, or Homarus americanus,
crab species selected from Carcinus maenas, Portunus pelagicus, Portunus trituberculatus, Callinectes sapidus, Cancer pagurus, Metacarcinus magister, or Chionoecetes;
crawfish species selected from Procambarus clarkii or Procambarus zonangulus; and
shrimp species selected from Penaeus monodon, Pandalus borealis, Acetes japonicas, or Trachysalambria curvirostris;
wherein hemocyanin is about 20% by weight based on the total weight of the composition; and
(b) administering the composition to the mammal;
whereby the skin is regenerated, repaired, or the function is restored to normal.