US 12,433,905 B2
Stable oral composition of cyclophosphamide
Venkataramana Naidu, Ahmedabad (IN); Jwalant Vijaybhai Desai, Ahmedabad (IN); Mayank Saxena, Ahmedabad (IN); and Ashutosh Jamloki, Ahmedabad (IN)
Assigned to INTAS PHARMACEUTICALS LTD., Gujarat (IN)
Appl. No. 17/625,649
Filed by INTAS PHARMACEUTICALS LTD., Gujarat Ahmedabad (IN)
PCT Filed Jul. 9, 2020, PCT No. PCT/IB2020/056450
§ 371(c)(1), (2) Date Jan. 7, 2022,
PCT Pub. No. WO2021/005544, PCT Pub. Date Jan. 14, 2021.
Claims priority of application No. 201921027551 (IN), filed on Jul. 10, 2019.
Prior Publication US 2022/0265688 A1, Aug. 25, 2022
Int. Cl. A61K 31/675 (2006.01); A61K 9/00 (2006.01); A61K 47/26 (2006.01)
CPC A61K 31/675 (2013.01) [A61K 9/0095 (2013.01); A61K 47/26 (2013.01)] 13 Claims
 
1. A stable oral composition of cyclophosphamide comprising: (a) a powder blend of cyclophosphamide and mannitol, and (b) a diluent, wherein the powder comprising cyclophosphamide is not obtained by lyophilization.