	US 12,433,864 B2
	5,6-diHETE lactone for treatment of microvascular dysfunction
Andrea Szuchman-Sapir, Upper Galilee (IL)
Assigned to MIGAL GALILEE RESEARCH INSTITUTE LTD., Kiryat Shmona (IL)
Appl. No. 17/615,670
Filed by MIGAL GALILEE RESEARCH INSTITUTE LTD., Kiryat Shmona (IL)
PCT Filed Jun. 2, 2020, PCT No. PCT/IL2020/050610 § 371(c)(1), (2) Date Dec. 1, 2021, PCT Pub. No. WO2020/245816, PCT Pub. Date Dec. 10, 2020.
Claims priority of provisional application 62/856,266, filed on Jun. 3, 2019.
Prior Publication US 2022/0241233 A1, Aug. 4, 2022
Int. Cl. A61K 31/202 (2006.01); A61K 9/00 (2006.01); A61P 9/12 (2006.01)

CPC A61K 31/202 (2013.01) [A61K 9/0019 (2013.01); A61P 9/12 (2018.01)]

6 Claims

1. A method of inducing vasodilation in a subject in need thereof, comprising administering to the subject 5,6 dihydroxyeicosatetraenoic acid (5,6-diHETE) lactone or a pharmaceutical composition comprising said 5,6-diHETE lactone.