US 12,433,842 B2
Pediatric dosage forms, methods of making and using
Praful Balavant Deshpande, Waterford (IE); Stephen James Quinlan, Waterford (IE); Marta Golec, Waterford (IE); John Gerard O'Brien, Waterford (IE); James Joseph McDonald, Waterford (IE); Reem Elamein Elsiddig, Waterford (IE); and Ken O'Shea, Waterford (IE)
Assigned to EIRGEN PHARMA LTD., Waterford (IE)
Filed by EIRGEN PHARMA LTD., Waterford (IE)
Filed on Apr. 7, 2021, as Appl. No. 17/224,768.
Application 17/224,768 is a continuation of application No. 16/869,273, filed on May 7, 2020, granted, now 11,000,480.
Application 16/869,273 is a continuation of application No. PCT/IB2019/057360, filed on Aug. 30, 2019.
Claims priority of provisional application 62/725,940, filed on Aug. 31, 2018.
Prior Publication US 2021/0401752 A1, Dec. 30, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 9/16 (2006.01); A61K 9/00 (2006.01); A61K 9/50 (2006.01); A61K 31/592 (2006.01); A61K 31/593 (2006.01); A61P 3/02 (2006.01); A61P 5/20 (2006.01); A61P 13/12 (2006.01)
CPC A61K 9/1652 (2013.01) [A61K 9/0002 (2013.01); A61K 9/0053 (2013.01); A61K 9/1617 (2013.01); A61K 9/1635 (2013.01); A61K 9/1694 (2013.01); A61K 31/592 (2013.01); A61K 31/593 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A solid extended release oral dosage form, the dosage form comprising a 25-hydroxyvitamin D compound in a solid hydrophilic matrix comprising
about 30 wt. % to about 50 wt. % microcrystalline cellulose;
about 5 wt. % to about 60 wt. % ethylcellulose;
about 5 wt. % to about 40 wt. % glyceryl behenate;
about 1 wt. % to about 20 wt. % polyglycolized glycerides; and
about 1 wt. % to about 15 wt. % methylcellulose.