US 12,433,744 B2
Percutaneous prosthetic device for replacing a mitral valve
Keysun Alizadehranjbar, Edmonton (CA)
Assigned to The Governors of the University of Alberta, (CA)
Appl. No. 17/438,106
Filed by The Governors of the University of Alberta, Edmonton (CA)
PCT Filed Mar. 10, 2020, PCT No. PCT/CA2020/050318
§ 371(c)(1), (2) Date Sep. 10, 2021,
PCT Pub. No. WO2020/181373, PCT Pub. Date Sep. 17, 2020.
Claims priority of provisional application 62/817,592, filed on Mar. 13, 2019.
Prior Publication US 2022/0183828 A1, Jun. 16, 2022
Int. Cl. A61F 2/24 (2006.01)
CPC A61F 2/2418 (2013.01) [A61F 2/2421 (2013.01); A61F 2210/009 (2013.01); A61F 2230/0065 (2013.01)] 12 Claims
OG exemplary drawing
 
1. A device for replacing a mitral valve comprising:
a substantially cylindrically-shaped body comprising a top portion, a bottom portion, and a waist portion disposed therebetween and having a plurality of ferromagnetic elements arranged circumferentially, the top portion and waist portion seatable within an annulus of the mitral valve and the bottom portion extendable below the annulus into a left ventricle, the body implantable percutaneously without surgical sutures or anchors, and the top portion, waist portion, and bottom portion defining an aperture extending therethrough for allowing blood flow; and
a separate clamping ring formed of a ferromagnetic material and comprising a pair of arms and a semi-circular ring supporting a plurality of perforated ferromagnetic spheres threaded thereon, the clamping ring being of sufficient length to be extendable through a coronary sinus and encircle the body from outside the annulus;
the clamping ring, the ferromagnetic spheres, and the ferromagnetic elements being attractable magnetically (i) to shape and stably anchor the body within the annulus (ii) to prevent dislodgement of the body upwardly into the left atrium due to increased pressure during diastole, and (iii) to block backflow of blood from the left ventricle through the aperture into the left atrium during systole.