US 12,433,734 B2
Microstructure soft tissue graft
Lukas Bluecher, Eurasberg (DE); and Michael Milbocker, Holliston, MA (US)
Assigned to BVW Holding AG, Cham (CH)
Filed by BVW Holding AG, Cham (CH)
Filed on May 2, 2023, as Appl. No. 18/142,244.
Application 18/142,244 is a continuation of application No. 16/862,531, filed on Apr. 29, 2020, granted, now 11,672,635.
Prior Publication US 2023/0263614 A1, Aug. 24, 2023
Int. Cl. A61F 2/00 (2006.01)
CPC A61F 2/0063 (2013.01) [A61F 2002/0068 (2013.01); A61F 2210/0004 (2013.01); A61F 2210/0076 (2013.01); A61F 2220/0016 (2013.01); A61F 2250/0031 (2013.01)] 15 Claims
OG exemplary drawing
 
1. An implantable soft tissue mesh device comprising:
a tissue scaffold layer comprising a biocompatible, non-bioabsorbable polymeric mesh;
a fixation layer comprising a first microstructured pattern, the fixation layer anchored to the tissue scaffold layer, wherein the first microstructured pattern comprises a first microfeature and a second microfeature arranged hierarchically, the first microfeature being from 10 to 100 microns in width, the second microfeature disposed about the first microfeature and being from 10 to 50 microns in width, wherein the fixation layer further comprises fenestrations allowing for tissue ingrowth, and wherein the fixation layer comprises a second microstructured pattern having a barbed microfeature configured to invasively engage a contact surface;
a filament disposed about the tissue scaffold layer and fixation layer for anchoring the fixation layer to the tissue scaffold layer;
wherein the fixation layer is configured to generate a Wenzel-Cassie interface with the contact surface and wherein a single barbed microfeature of the second microstructured pattern exerts no more than 0.025 kg/cm3 of the volume of the single barbed microfeature and a separation force exceeds 25 kg/cm2 of a contact area between the implantable soft tissue mesh device and the contact surface when the implantable soft tissue mesh device is separated from the contact surface.