| CPC A61B 34/20 (2016.02) [A61B 5/067 (2013.01); A61B 5/6861 (2013.01); A61B 2034/2055 (2016.02)] | 10 Claims |

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1. An ingestible in-vivo gastrointestinal device comprising:
a power source;
a processor and a memory; and
at least one sensor, configured to provide sensor signals indicative of the device in a digestive tract of a subject,
the processor, configured to sequentially determine a location of the in-vivo gastrointestinal device as being in one of an esophagus, a stomach, a small intestine and a large intestine of the subject, responsive to the received signals,
wherein the processor is configured to determine the location of the device as being in the esophagus or the small intestine, responsive to a dominant single axis movement of the device for at least a predetermined minimum time, and to determine the location of the device as being in the stomach or the large intestine, responsive to a multi-axis movement of the device for at least a predetermined minimum time.
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