US 12,433,670 B2
Systems and methods for treating cancer and/or augmenting organ function
Landy Toth, Doylestown, PA (US); and Robert S. Schwartz, Inver Grove Heights, MN (US)
Assigned to Autonomix Medical, Inc., Ivyland, PA (US)
Filed by Autonomix Medical, Inc., Excelsior, MN (US)
Filed on Jun. 7, 2022, as Appl. No. 17/833,964.
Application 17/833,964 is a continuation of application No. 16/158,385, filed on Oct. 12, 2018, granted, now 11,382,687.
Application 16/158,385 is a continuation of application No. 14/958,659, filed on Dec. 3, 2015, granted, now 10,136,944, issued on Nov. 27, 2018.
Application 14/958,659 is a continuation in part of application No. 14/895,744, granted, now 10,143,419, issued on Dec. 4, 2018, previously published as PCT/US2014/060471, filed on Oct. 14, 2014.
Claims priority of provisional application 62/087,629, filed on Dec. 4, 2014.
Claims priority of provisional application 62/010,699, filed on Jun. 11, 2014.
Claims priority of provisional application 61/891,242, filed on Oct. 15, 2013.
Prior Publication US 2022/0296296 A1, Sep. 22, 2022
Int. Cl. A61B 18/14 (2006.01); A61B 18/02 (2006.01); A61B 18/00 (2006.01); A61B 18/18 (2006.01)
CPC A61B 18/1492 (2013.01) [A61B 2018/0022 (2013.01); A61B 2018/00267 (2013.01); A61B 2018/00404 (2013.01); A61B 2018/00434 (2013.01); A61B 2018/00773 (2013.01); A61B 2018/00839 (2013.01); A61B 2018/0212 (2013.01); A61B 18/1815 (2013.01); A61M 2205/051 (2013.01); A61M 2205/058 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A medical system, comprising:
a microsurgical tool dimensioned for insertion into a lumen with a wall, the lumen being in fluid communication with a target region of a subject, wherein the target region comprises at least one of one or more nerves and one or more lymphatic ducts coupled to at least one of a tumor and a metastatic cell within a body of the subject, the microsurgical tool comprising:
a distal tip configured to interface with the wall of the lumen, the distal tip comprising (i) one or more delivery means configured to apply a block to the target region and (ii) one or more microfingers equipped with a plurality of sensing points, the distal tip having one or more dimensions configured to facilitate placement into the lumen; and
a controller configured:
to deploy the one or more microfingers such that at least a subset of the plurality of sensing points interface with the wall of the lumen;
to retract the one or more microfingers such that at least the subset of the plurality of sensing points drag along the wall of the lumen;
to map electrophysiological information along the wall of the lumen based at least in part on signals recorded by the subset of the plurality of sensing points while the one or more microfingers are retracted; and
to control operation of the one or more delivery means based at least in part on the mapped electrophysiological information.