US 12,433,485 B2
Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
Peter C. Simpson, San Diego, CA (US); Robert J. Boock, Carlsbad, CA (US); Mark C. Brister, Cardiff, CA (US); Monica A. Rixman Swinney, Medford, MA (US); Kum Ming Woo, San Diego, CA (US); Lisa Nguyen, San Diego, CA (US); Seth R. Brunner, San Diego, CA (US); Arthur Chee, San Diego, CA (US); Melissa A. Nicholas, Monterey, CA (US); Matthew D. Wightlin, San Diego, CA (US); Jack Pryor, San Diego, CA (US); and Dubravka Markovic, San Diego, CA (US)
Assigned to Dexcom, Inc., San Diego, CA (US)
Filed by DexCom, Inc., San Diego, CA (US)
Filed on Sep. 1, 2020, as Appl. No. 17/009,463.
Application 17/009,463 is a continuation of application No. 16/796,830, filed on Feb. 20, 2020, granted, now 10,791,928.
Application 16/796,830 is a continuation of application No. 16/599,072, filed on Oct. 10, 2019, abandoned.
Application 16/599,072 is a continuation of application No. 16/453,925, filed on Jun. 26, 2019, abandoned.
Application 16/453,925 is a continuation of application No. 14/145,404, filed on Dec. 31, 2013, granted, now 10,376,143.
Application 14/145,404 is a continuation of application No. 13/732,848, filed on Jan. 2, 2013, granted, now 9,763,609.
Application 13/732,848 is a continuation of application No. 11/750,907, filed on May 18, 2007, granted, now 8,364,229.
Prior Publication US 2020/0397291 A1, Dec. 24, 2020
Int. Cl. A61B 5/145 (2006.01); A61B 5/00 (2006.01); A61B 5/1473 (2006.01); A61B 5/1486 (2006.01)
CPC A61B 5/00 (2013.01) [A61B 5/14532 (2013.01); A61B 5/14546 (2013.01); A61B 5/1473 (2013.01); A61B 5/14735 (2013.01); A61B 5/1486 (2013.01); A61B 5/14865 (2013.01); A61B 5/6848 (2013.01); A61B 5/7203 (2013.01)] 28 Claims
OG exemplary drawing
 
1. A glucose sensor configured for implantation in a host, the glucose sensor comprising:
an ex vivo portion and an in vivo portion, wherein the in vivo portion comprises:
a reference electrode disposed at least in part on the in vivo portion of the glucose sensor,
an electrode comprising a plurality of electroactive surfaces each configured to measure a signal indicative of a glucose concentration of the host, wherein the signal comprises a glucose-related component and a non-glucose related component, wherein the plurality of electroactive surfaces comprise a first electroactive surface, a second electroactive surface, and a third electroactive surface spaced along a length of the in vivo portion;
an enzyme configured to react with glucose; and
a membrane covering at least a portion of the electrode and the enzyme, wherein the membrane comprises an outer domain formed from a blend comprising at least 5 wt. % of a hydrophilic component,
wherein the first electroactive surface, the second electroactive surface, and the third electroactive surface share a central axis, wherein the central axis is an axis of sensor insertion.