US 12,106,476 B2
Technique for assigning a perfusion metric to DCE MR images
Ingmar Voigt, Erlangen (DE); Marcel Dominik Nickel, Herzogenaurach (DE); Tommaso Mansi, Plainsboro, NJ (US); and Sebastien Piat, Lawrence Township, NJ (US)
Assigned to Siemens Healthineers AG, Forchheim (DE)
Filed by SIEMENS HEALTHINEERS AG, Forchheim (DE)
Filed on May 5, 2022, as Appl. No. 17/662,088.
Claims priority of application No. 21175153 (EP), filed on May 21, 2021.
Prior Publication US 2022/0375073 A1, Nov. 24, 2022
Int. Cl. G06T 7/00 (2017.01); G06N 3/04 (2023.01); G06T 5/92 (2024.01); G06T 7/30 (2017.01)
CPC G06T 7/0012 (2013.01) [G06N 3/04 (2013.01); G06T 5/92 (2024.01); G06T 7/30 (2017.01); G06T 2207/10088 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/20084 (2013.01); G06T 2207/30096 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A neural network system for assigning at least one perfusion metric to dynamic contrast-enhanced (DCE) magnetic resonance (MR) images, the DCE MR images obtained from a MR scanner and under a free-breathing protocol, the neural network system comprising:
an input layer configured to receive at least one DCE MR image representative of a first contrast enhancement state and of a first respiratory motion state and at least one further DCE MR image representative of a second contrast enhancement state and of a second respiratory motion state; and
an output layer configured to output at least one perfusion metric based on the at least one DCE MR image and the at least one further DCE MR image,
wherein the neural network system with interconnections between the input layer and the output layer was trained by a plurality of datasets, each of the datasets comprising an instance of the at least one DCE MR image and of the at least one further DCE MR image for the input layer (114) and the at least one perfusion metric for the output layer; and
wherein the neural network comprises a first sub-network and a second sub-network, and wherein the interconnections comprise cross-connection between the first sub-network and the second sub-network at the input layer and/or at least one hidden layer between the input layer and the output layer.