| CPC G06T 7/0012 (2013.01) [G06T 7/11 (2017.01); G06T 7/50 (2017.01); G06T 2207/10101 (2013.01); G06T 2207/30024 (2013.01); G06T 2207/30044 (2013.01)] | 10 Claims |
|
1. An image processing method for an image of a cell aggregate with a cavity inside as a processing object, the image processing method comprising:
obtaining three-dimensional image data representing a three-dimensional image of the cell aggregate obtained by optical coherence tomography imaging;
obtaining a thickness distribution representing a thickness of the cell aggregate between an outer surface of the cell aggregate facing an outside space and an inner surface thereof facing the cavity at each position based on the three-dimensional image data; and
detecting protrusion parts having a prominent thickness as compared to a surrounding region based on the thickness distribution,
wherein polar coordinate data representing a position of each point of the cell aggregate as a position in a polar coordinate space are generated from three-dimensional image data,
wherein the thickness distribution of the cell aggregate is obtained based on the polar coordinate data,
wherein each of the protrusion parts is detected based on a thickness profile of the cell aggregate associating a radial direction in the polar coordinate space and the thickness of the cell aggregate obtained in this radial direction,
wherein a maximum value filter processing is applied to the thickness profile, and
wherein a position where there is no change in value before and after the maximum value filter processing is detected as a position of the protrusion part.
|