US 12,105,105 B2
Systems and methods for pipette robots
Andrew Sigler, Brooklyn, NY (US); Taylor Schlaff Goodman, New York, NY (US); Nicholas Pease Starno, Fort Pierce, FL (US); and Jonathan Preston Badal, Brooklyn, NY (US)
Assigned to Opentrons Labworks Inc., Brooklyn, NY (US)
Filed by Opentrons Labworks Inc., Brooklyn, NY (US)
Filed on Oct. 24, 2022, as Appl. No. 17/972,067.
Application 17/972,067 is a continuation of application No. 16/722,749, filed on Dec. 20, 2019, granted, now 11,506,677.
Claims priority of provisional application 62/784,135, filed on Dec. 21, 2018.
Prior Publication US 2023/0041126 A1, Feb. 9, 2023
Int. Cl. B01L 3/02 (2006.01); G01N 35/00 (2006.01); G01N 35/10 (2006.01)
CPC G01N 35/0099 (2013.01) [B01L 3/0227 (2013.01); B01L 3/0237 (2013.01); G01N 35/00693 (2013.01); G01N 35/1011 (2013.01)] 4 Claims
OG exemplary drawing
 
1. A pipette robot, comprising:
a computer, wherein said computer comprises:
at least one processor; and
a memory including instructions;
a frame;
a deck operatively connected to the frame;
a gantry operatively connected to the frame; and
a pipette operatively connected to the gantry;
a motor operatively connected to the gantry, wherein the motor is further operatively connected to the at least one processor;
a contact recognition electronic device operatively connected to the pipette; and
jog controls operatively connected to the at least one processor,
wherein the instructions, when executed by the at least one processor of the computer, cause:
moving, using the gantry, the pipette to a first point on the deck, wherein the pipette is moved to within on order of 1 cm from the first point on the deck;
providing, using one or more of the contact recognition electronic device or the jog controls, for jogging of the pipette relative to the first point on the deck,
wherein said jogging relative to the first point on the deck centers a tip of the pipette with the first point on the deck;
determining, using the at least one processor, an XYZ coordinate of the first point on the deck;
moving, using the gantry, the pipette to a second point on the deck, wherein the pipette is moved to within on order of 1 cm from the second point on the deck;
providing, using one or more of the contact recognition electronic device or the jog controls, for jogging of the pipette relative to the second point on the deck, wherein said jogging relative to the second point on the deck centers said pipette tip with the second point on the deck;
determining, using the at least one processor, an XYZ coordinate of the second point on the deck;
moving, using the gantry, the pipette to a third point on the deck, wherein the pipette is moved to within on order of 1 cm from the third point on the deck:
providing, using one or more of the contact recognition electronic device or the jog controls, for jogging of the pipette relative to the third point on the deck, wherein said jogging relative to the third point on the deck centers said pipette tip with the third point on the deck;
determining, using the at least one processor, an XYZ coordinate of the third point on the deck;
determining, using the at least one processor, based on said movement to the second point on the deck, an adjustment multiplier X-axis scale;
determining, using the at least one processor, based on said movement to the third point on the deck, an adjustment multiplier Y-axis scale; and
performing liquid handling operations, wherein the pipette is moved using the gantry, and wherein said movement of the gantry is adjusted using one or more of the adjustment multiplier X-axis scale or the adjustment multiplier Y-axis scale.