US 12,105,072 B2
Chemical sensor, detection method, reagent and kit
Yoshiaki Sugizaki, Kanagawa (JP)
Assigned to KABUSHIKI KAISHA TOSHIBA, Tokyo (JP)
Filed by KABUSHIKI KAISHA TOSHIBA, Tokyo (JP)
Filed on Apr. 17, 2023, as Appl. No. 18/301,613.
Application 18/301,613 is a division of application No. 16/812,423, filed on Mar. 9, 2020.
Claims priority of application No. 2019-168322 (JP), filed on Sep. 17, 2019.
Prior Publication US 2023/0273165 A1, Aug. 31, 2023
Int. Cl. G01N 33/00 (2006.01); C12Q 1/00 (2006.01); G01N 1/44 (2006.01); G01N 27/49 (2006.01); G01N 1/28 (2006.01)
CPC G01N 33/0013 (2013.01) [C12Q 1/005 (2013.01); G01N 1/44 (2013.01); G01N 27/49 (2013.01); G01N 2001/2833 (2013.01); G01N 33/0042 (2013.01); G01N 33/0047 (2013.01)] 21 Claims
OG exemplary drawing
 
1. A chemical sensor comprising:
a sensor element comprising a sensitive film whose physical properties vary as bonding or approachment of a target substance to the sensitive film,
wherein the sensor element is configured to detect a variation in the physical properties of the sensitive film; and
a treatment material which is configured to carry out a treatment onto the target substance before the target substance bonds to or approaches the sensitive film wherein the treatment material comprises an enzyme having an activity to carry out the treatment onto the target substance and a cofactor of the enzyme,
the treatment enhancing the variation in the physical properties as compared to a case without the treatment.