	US 12,104,181 B2
	Compositions and methods for treating viral infections targeting TRIM7
John W. Schoggins, Dallas, TX (US); Wenchun Fan, Dallas, TX (US); Daniel J. Siegwart, Dallas, TX (US); and Qiang Cheng, Dallas, TX (US)
Assigned to The Board of Regents of The University of Texas System, Austin, TX (US)
Filed by THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US)
Filed on Mar. 31, 2022, as Appl. No. 17/710,464.
Claims priority of provisional application 63/168,898, filed on Mar. 31, 2021.
Prior Publication US 2022/0325255 A1, Oct. 13, 2022
Int. Cl. A61P 31/14 (2006.01); A61K 9/51 (2006.01); A61K 48/00 (2006.01); C12N 9/10 (2006.01)

CPC C12N 9/104 (2013.01) [A61K 9/5123 (2013.01); A61K 48/0066 (2013.01); A61P 31/14 (2018.01)]

10 Claims

1. A method of treating an enterovirus infection, comprising administering to a subject a composition comprising at least one mRNA encoding a tripartite motif containing 7 (TRIM7) protein and at least one lipid nanoparticle (LNP), wherein the subject has or is suspected of having an enterovirus infection.