	US 12,104,069 B2
	Epidermal penetration type ink composition
Seok-ki Kim, Goyang-si (KR); Sang Hyuk Lee, Daegu (KR); and Jin Hee Noh, Goyang-si (KR)
Assigned to NATIONAL CANCER CENTER, Goyang-si (KR)
Appl. No. 16/755,359
Filed by NATIONAL CANCER CENTER, Goyang-si (KR)
PCT Filed Oct. 1, 2018, PCT No. PCT/KR2018/011662 § 371(c)(1), (2) Date Apr. 10, 2020, PCT Pub. No. WO2019/074229, PCT Pub. Date Apr. 18, 2019.
Claims priority of application No. 10-2017-0131508 (KR), filed on Oct. 11, 2017.
Prior Publication US 2021/0139731 A1, May 13, 2021
Int. Cl. C09D 11/50 (2014.01); A61K 49/00 (2006.01); C09D 11/17 (2014.01); C09D 11/20 (2006.01)

CPC C09D 11/50 (2013.01) [A61K 49/0023 (2013.01); A61K 49/0028 (2013.01); A61K 49/0032 (2013.01); A61K 49/0034 (2013.01); A61K 49/0054 (2013.01); C09D 11/17 (2013.01); C09D 11/20 (2013.01)]

4 Claims

1. An ink composition which penetrates into the stratum corneum of the skin, comprising:

a fluorescent colorant, wherein the fluorescent colorant is indocyanine green (ICG);

a binder resin, wherein the binder resin is a combination of polyvinylpyrrolidone (PVP) and polyvinyl butyral (PVB); and

a solvent, wherein the solvent is ethanol,

wherein a concentration of fluorescent colorant is in the range of 0.02 mM to 20 mM, a concentration of the combination of PVP and PVB is the range of 3 to 5 wt % relative to the total composition of 100 wt %, and an amount of the ethanol is in the range of 5 to 10 wt % relative to the total composition of 100 wt %.