US 12,103,939 B2
Solid pharmaceutical gold-based composition
Anvarhusein A. Isab, Dhahran (SA); and Adam Ahmed Abdullah Sulaiman, Dhahran (SA)
Assigned to KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, Dhahran (SA)
Filed by KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, Dhahran (SA)
Filed on Mar. 15, 2024, as Appl. No. 18/606,260.
Application 18/606,260 is a continuation of application No. 17/825,009, filed on May 26, 2022, granted, now 11,958,867.
Application 17/825,009 is a continuation of application No. 16/554,224, filed on Aug. 28, 2019, granted, now 11,384,100, issued on Jul. 12, 2022.
Prior Publication US 2024/0279242 A1, Aug. 22, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. A61P 35/00 (2006.01); C07F 1/00 (2006.01)
CPC C07F 1/005 (2013.01) [A61P 35/00 (2018.01)] 5 Claims
 
1. A solid pharmaceutical composition in the form of a tablet, comprising:
a gold (III) complex of formula (I),

OG Complex Work Unit Chemistry
and/or a pharmaceutically acceptable salt thereof, and
a pharmaceutically acceptable carrier selected from the group consisting of talc magnesium, calcium stearate, zinc stearate, steric acid, lactose, corn starch, sodium carboxymethyl cellulose, ethyl cellulose, and cellulose acetate;
wherein:
R1 and R2 are each independently a hydrogen or an optionally substituted arylalkyl;
R3 and R4 are each independently a hydrogen, an optionally substituted alkoxy, or a hydroxyl; and
X is Cl or Br.