US 12,103,907 B2
	Tetralin and tetrahydroquinoline compounds as inhibitors of HIF-2alpha
Joel Worley Beatty, San Mateo, CA (US); Samuel Lawrie Drew, Millbrae, CA (US); Matthew Epplin, South San Francisco, CA (US); Jeremy Thomas Andre Fournier, Fremont, CA (US); Balint Gal, Hayward, CA (US); Tezcan Guney, Hayward, CA (US); Karl T. Haelsig, Berkeley, CA (US); Clayton Hardman, San Francisco, CA (US); Steven Donald Jacob, Oakland, CA (US); Jenna Leigh Jeffrey, Oakland, CA (US); Jaroslaw Kalisiak, Mountain View, CA (US); Kenneth Victor Lawson, San Francisco, CA (US); Manmohan Reddy Leleti, Dublin, CA (US); Erick Allen Lindsey, San Diego, CA (US); Artur Karenovich Mailyan, Hayward, CA (US); Debashis Mandal, Fremont, CA (US); Guillaume Mata, Berkeley, CA (US); Hyunyoung Moon, Foster City, CA (US); Jay Patrick Powers, Sisters, OR (US); Brandon Reid Rosen, San Mateo, CA (US); Yongli Su, Foster City, CA (US); Anh Thu Tran, Union City, CA (US); Zhang Wang, Petaluma, CA (US); Xuelei Yan, Foster City, CA (US); and Kai Yu, Hayward, CA (US)
Assigned to Arcus Biosciences, Inc., Hayward, CA (US)
Filed by ARCUS BIOSCIENCES, INC., Hayward, CA (US)
Filed on Aug. 30, 2023, as Appl. No. 18/239,892.
Application 17/835,559 is a division of application No. 17/205,273, filed on Mar. 18, 2021, granted, now 11,407,712, issued on Aug. 9, 2022.
Application 18/239,892 is a continuation of application No. 17/835,559, filed on Jun. 8, 2022, granted, now 11,787,762.
Claims priority of provisional application 63/120,875, filed on Dec. 3, 2020.
Claims priority of provisional application 62/991,952, filed on Mar. 19, 2020.
Prior Publication US 2024/0254079 A1, Aug. 1, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. C07C 317/32 (2006.01); A61K 31/10 (2006.01); A61K 31/277 (2006.01); A61K 31/343 (2006.01); A61K 31/353 (2006.01); A61K 31/365 (2006.01); A61K 31/381 (2006.01); A61K 31/404 (2006.01); A61K 31/415 (2006.01); A61K 31/416 (2006.01); A61K 31/4174 (2006.01); A61K 31/4192 (2006.01); A61K 31/4196 (2006.01); A61K 31/421 (2006.01); A61K 31/423 (2006.01); A61K 31/426 (2006.01); A61K 31/428 (2006.01); A61K 31/437 (2006.01); A61K 31/44 (2006.01); A61K 31/4412 (2006.01); A61K 31/47 (2006.01); A61K 31/4709 (2006.01); A61K 31/472 (2006.01); A61K 31/4965 (2006.01); A61K 31/50 (2006.01); A61K 31/5025 (2006.01); A61K 31/505 (2006.01); A61K 31/519 (2006.01); A61K 31/538 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); C07C 255/53 (2006.01); C07C 317/22 (2006.01); C07C 317/36 (2006.01); C07D 209/34 (2006.01); C07D 211/86 (2006.01); C07D 213/57 (2006.01); C07D 213/71 (2006.01); C07D 213/73 (2006.01); C07D 213/74 (2006.01); C07D 213/84 (2006.01); C07D 215/48 (2006.01); C07D 217/04 (2006.01); C07D 231/12 (2006.01); C07D 231/56 (2006.01); C07D 233/64 (2006.01); C07D 237/20 (2006.01); C07D 239/42 (2006.01); C07D 241/12 (2006.01); C07D 249/06 (2006.01); C07D 249/08 (2006.01); C07D 263/32 (2006.01); C07D 263/57 (2006.01); C07D 265/36 (2006.01); C07D 277/30 (2006.01); C07D 277/56 (2006.01); C07D 277/64 (2006.01); C07D 307/83 (2006.01); C07D 311/22 (2006.01); C07D 333/64 (2006.01); C07D 401/04 (2006.01); C07D 401/10 (2006.01); C07D 409/10 (2006.01); C07D 413/10 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01)

CPC C07C 317/32 (2013.01) [A61K 31/10 (2013.01); A61K 31/277 (2013.01); A61K 31/343 (2013.01); A61K 31/353 (2013.01); A61K 31/365 (2013.01); A61K 31/381 (2013.01); A61K 31/404 (2013.01); A61K 31/415 (2013.01); A61K 31/416 (2013.01); A61K 31/4174 (2013.01); A61K 31/4192 (2013.01); A61K 31/4196 (2013.01); A61K 31/421 (2013.01); A61K 31/423 (2013.01); A61K 31/426 (2013.01); A61K 31/428 (2013.01); A61K 31/437 (2013.01); A61K 31/44 (2013.01); A61K 31/4412 (2013.01); A61K 31/47 (2013.01); A61K 31/4709 (2013.01); A61K 31/472 (2013.01); A61K 31/4965 (2013.01); A61K 31/50 (2013.01); A61K 31/5025 (2013.01); A61K 31/505 (2013.01); A61K 31/519 (2013.01); A61K 31/538 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07C 255/53 (2013.01); C07C 317/22 (2013.01); C07C 317/36 (2013.01); C07D 209/34 (2013.01); C07D 211/86 (2013.01); C07D 213/57 (2013.01); C07D 213/71 (2013.01); C07D 213/73 (2013.01); C07D 213/74 (2013.01); C07D 213/84 (2013.01); C07D 215/48 (2013.01); C07D 217/04 (2013.01); C07D 231/12 (2013.01); C07D 231/56 (2013.01); C07D 233/64 (2013.01); C07D 237/20 (2013.01); C07D 239/42 (2013.01); C07D 241/12 (2013.01); C07D 249/06 (2013.01); C07D 249/08 (2013.01); C07D 263/32 (2013.01); C07D 263/57 (2013.01); C07D 265/36 (2013.01); C07D 277/30 (2013.01); C07D 277/56 (2013.01); C07D 277/64 (2013.01); C07D 307/83 (2013.01); C07D 311/22 (2013.01); C07D 333/64 (2013.01); C07D 401/04 (2013.01); C07D 401/10 (2013.01); C07D 409/10 (2013.01); C07D 413/10 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07C 2602/08 (2017.05); C07C 2602/10 (2017.05)]

1 Claim

1. A compound having the formula: