US 12,102,708 B2
Treatment method for teeth and gums
Abdul Samad Khan, Dammam (SA)
Assigned to Imam Abdulrahman Bin Faisal University, Dammam (SA)
Filed by Imam Abdulrahman Bin Faisal University, Dammam (SA)
Filed on Mar. 9, 2024, as Appl. No. 18/600,658.
Application 18/600,658 is a continuation of application No. 18/336,433, filed on Jun. 16, 2023, granted, now 11,957,782.
Application 18/336,433 is a continuation of application No. 17/705,904, filed on Mar. 28, 2022, granted, now 11,744,795, issued on Sep. 5, 2023.
Application 17/705,904 is a continuation of application No. 16/252,039, filed on Jan. 18, 2019, granted, now 11,318,087, issued on May 3, 2022.
Prior Publication US 2024/0225996 A1, Jul. 11, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 8/9789 (2017.01); A61K 8/25 (2006.01); A61K 8/27 (2006.01); A61K 8/29 (2006.01); A61K 8/34 (2006.01); A61K 8/368 (2006.01); A61K 8/46 (2006.01); A61K 8/73 (2006.01); A61Q 11/00 (2006.01)
CPC A61K 8/9789 (2017.08) [A61K 8/25 (2013.01); A61K 8/27 (2013.01); A61K 8/29 (2013.01); A61K 8/345 (2013.01); A61K 8/368 (2013.01); A61K 8/463 (2013.01); A61K 8/731 (2013.01); A61Q 11/00 (2013.01); A61K 2800/28 (2013.01); A61K 2800/48 (2013.01); A61K 2800/524 (2013.01)] 5 Claims
 
1. A gum and tooth treatment method to control tooth sensitivity, comprising:
brushing the teeth of a subject with a toothpaste composition to passivate the surface of tooth dentin of the subject to reduce dentin tubule openings, and
contacting the gums of the subject with the toothpaste composition,
wherein the teeth of the subject are brushed for a time of at least one minute;
wherein the toothpaste composition comprises:
(a) Nigella sativa oil in an amount of 3 wt. %;
(b) an amount of water in the range of 33 wt. % to 36 wt. %;
(c) sodium lauryl sulfate in the range of 1 wt. % to 2 wt. %,
(d) glycerol in the range of 29 wt. % to 32 wt. %,
(e) sodium benzoate in the range of 0.5% to 1.0 wt. %,
(f) methyl cellulose in the range of 0.5% to 1.0 wt. %,
(g) calcium carbonate in the range of 24 wt. % to 27 wt. %,
(h) flavoring agent in the range of 0.5% to 1.0 wt. %,
(i) fluoride-doped bioactive glass in an amount of 1.5 wt. %;
(i) zinc oxide in an amount of 3.0 wt. %; and
(k) titanium oxide in an amount of 2 wt. %;
wherein the wt. % is present by weight of the total weight of the toothpaste and the toothpaste composition has a maximum mean bioglass fluoride release in elutes of 9.95 to 10.75 ppm.