US 12,102,659 B2
Methods for the prevention or treatment of heart failure
Hazel H. Szeto, New York, NY (US); Peter S. Rabinovitch, Shoreline, WA (US); and Dao-Fu Dai, Seattle, WA (US)
Assigned to CORNELL UNIVERSITY, Ithaca, NY (US); and UNIVERSITY OF WASHINGTON, Seattle, WA (US)
Filed by Cornell University, Ithaca, NY (US); and University of Washington, Seattle, WA (US)
Filed on Dec. 12, 2022, as Appl. No. 18/079,604.
Application 18/079,604 is a continuation of application No. 16/796,940, filed on Feb. 20, 2020, granted, now 11,534,476.
Application 16/796,940 is a continuation of application No. 15/723,259, filed on Oct. 3, 2017, abandoned.
Application 15/723,259 is a continuation of application No. 14/727,513, filed on Jun. 1, 2015, abandoned.
Application 14/727,513 is a continuation of application No. 14/035,577, filed on Sep. 24, 2013, abandoned.
Application 14/035,577 is a continuation of application No. 12/897,325, filed on Oct. 4, 2010, abandoned.
Claims priority of provisional application 61/289,483, filed on Dec. 23, 2009.
Claims priority of provisional application 61/248,681, filed on Oct. 5, 2009.
Prior Publication US 2023/0285499 A1, Sep. 14, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 38/07 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); A61P 9/00 (2006.01); C07K 5/09 (2006.01); C07K 5/107 (2006.01); C07K 5/11 (2006.01)
CPC A61K 38/07 (2013.01) [A61K 9/0019 (2013.01); A61K 45/06 (2013.01); A61P 9/00 (2018.01); C07K 5/0817 (2013.01); C07K 5/1016 (2013.01); C07K 5/1019 (2013.01)] 9 Claims
 
1. A method of treating hypertensive cardiomyopathy in a mammalian subject, comprising administering to the mammalian subject in need thereof a therapeutically effective amount of the peptide D-Arg-2′6′-Dmt-Lys-Phe-NH2.