US 12,102,650 B2
Anhydrous antimicrobial topical formulations and methods of use thereof
Ariel Antonio Franco, Yokneam Illit (IL); and Rajashekharayya A. Sanguramath, Yokneam Illit (IL)
Assigned to NSC-NANO SONO COOPERATION LTD, Yokneam, IL (US)
Filed by NSC—NANO SONO COOPERATION LTD, Yokneam Illit (IL)
Filed on Jul. 13, 2021, as Appl. No. 17/373,781.
Claims priority of provisional application 63/050,933, filed on Jul. 13, 2020.
Prior Publication US 2022/0008461 A1, Jan. 13, 2022
Int. Cl. A61K 33/34 (2006.01); A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61K 33/00 (2006.01); A61K 33/06 (2006.01); A61K 33/242 (2019.01); A61K 33/30 (2006.01); A61K 33/38 (2006.01); A61K 47/06 (2006.01); A61K 47/10 (2017.01); A61K 47/14 (2017.01); A61K 47/22 (2006.01); A61K 47/26 (2006.01); A61K 47/69 (2017.01); A61P 31/02 (2006.01)
CPC A61K 33/34 (2013.01) [A61K 9/0014 (2013.01); A61K 9/06 (2013.01); A61K 33/00 (2013.01); A61K 33/06 (2013.01); A61K 33/242 (2019.01); A61K 33/30 (2013.01); A61K 33/38 (2013.01); A61K 47/06 (2013.01); A61K 47/10 (2013.01); A61K 47/14 (2013.01); A61K 47/22 (2013.01); A61K 47/26 (2013.01); A61K 47/6935 (2017.08); A61P 31/02 (2018.01)] 3 Claims
 
1. A method for treating a wound by inhibiting microbial growth in or on the wound in a subject in need thereof comprising contacting a wound on the subject with a therapeutically effective amount of an antimicrobial topical ointment consisting of:
about 76.2 wt % polyethylene glycol (PEG)-400;
about 20 wt % PEG-4000;
about 0.4-1.0 wt % polysorbate-80;
about 1 wt % caprylic/capric triglycerides;
about 1 wt % α-Bisabolol; and
about 1 wt % CuO(1-x)ZnOx,
wherein the antimicrobial ointment inhibits microbial growth in or on the wound by at least 99%, thereby treating the wound.