| CPC A61K 31/519 (2013.01) [A61P 35/00 (2018.01)] | 19 Claims |
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1. A method of treating a brain cancer in a patient in need thereof, the method comprising:
administering to the patient a pharmaceutical composition comprising a therapeutically effective amount of compound (1)
 or a pharmaceutically acceptable salt thereof, at a predetermined dose with a frequency selected from one or more of:
a) once daily;
b) according to an infrequent dosing regimen;
c) according to a frequent dosing regimen;
d) once weekly;
e) once every four weeks;
f) twice a week;
g) once every two weeks;
h) once every three weeks; and
i) in a repeated cycle of once weekly, once every two weeks, once every three weeks, once every four weeks,
wherein the cancer has a histone H3 K27M mutation.
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