US 12,102,630 B2
Crystalline forms and processes of lenvatinib besylate
Luis Nogueiras Nieto, Sant Boi de Llobregat (ES); Lisardo Alvarez Fernandez, Sant Boi de Llobregat (ES); Raymond Westheim, Nijmegen (NL); and Katerina Jelinkova, Blansko (CZ)
Assigned to Synthon B.V., Nijmegen (NL)
Appl. No. 17/282,505
Filed by Synthon B.V., Nijmegen (NL)
PCT Filed Oct. 1, 2019, PCT No. PCT/EP2019/076622
§ 371(c)(1), (2) Date Apr. 2, 2021,
PCT Pub. No. WO2020/070144, PCT Pub. Date Apr. 9, 2020.
Claims priority of application No. 18198662 (EP), filed on Oct. 4, 2018; and application No. 19172395 (EP), filed on May 2, 2019.
Prior Publication US 2022/0062263 A1, Mar. 3, 2022
Int. Cl.
A61K 31/47
(2006.01);
A61K 9/48
(2006.01);
C07D 215/48
(2006.01)
CPC
A61K 31/47
(2013.01) [
A61K 9/485
(2013.01);
A61K 9/4858
(2013.01);
A61K 9/4866
(2013.01);
C07D 215/48
(2013.01);
C07B 2200/13
(2013.01)]
26 Claims
1. A lenvatinib besylate salt.